Storage conditions of empty capsules of Hydroxypropyl Methylcellulose

The storage conditions of empty capsules of hydroxypropyl methylcellulose are as follows:
It needs to be sealed and stored at room temperature to avoid high temperature and high humidity affecting the product properties. It should be stored in a cool, dry, clean, and light-shielded environment. It is strictly forbidden to mix with toxic and harmful substances.

Specifically, empty capsules of hydroxypropyl methylcellulose will not soften, deform, or harden and become brittle when the temperature is between 10 and 40°C and the humidity reaches 35 to 65%. The storage conditions are relatively wide. However, in order to ensure its optimal performance, it is still necessary to pay attention to the cool, dry, and light-shielded storage environment and prevent contact with toxic and harmful substances to avoid contamination.

Hydroxypropyl methylcellulose is hygroscopic after drying, but its properties are stable. Its solution is stable at pH 3-11. The viscosity of the solution decreases as the temperature increases. Heating and cooling can make hydroxypropyl methylcellulose reversibly transform from a solution state to a gel state. Depending on the grade and concentration, the gelation temperature is 50-90°C. However, its aqueous solution is susceptible to microbial invasion, so preservatives and antibacterial agents should be added during storage. When used as a viscosity enhancer in ophthalmic eye drops, benzalkonium chloride is usually added as a preservative, and the aqueous solution can be autoclaved. Its powder must be stored in a sealed container and placed in a cool and dry place. It can be inferred that when storing HPMC empty capsules, attention should be paid to moisture-proof and microbial contamination prevention, and high-temperature environments.