Enteric-coated hollow capsules must meet the alkaline liquid in the intestine to dissolve

Enteric-coated hollow capsules must meet the alkaline liquid in the intestine to dissolve, and gastric acid is acidic, so the capsules do not dissolve in the stomach. If enteric-coated capsules melt in the stomach, it may cause damage to the stomach. At present, the commonly used capsules in clinical practice are gelatin capsules composed of gelatin. Pharmaceutical gelatin is a high-quality adhesive made from animal skin, bones and tendons. It has undergone complex physical and chemical treatments. It has the physical characteristics of high viscosity, high freezing and easy freezing. The digestive organs of the body are mainly the stomach and intestines. The stomach is mainly acidic, and the intestines are alkaline. Therefore, according to this part, there are usually two capsules, one dissolves in the stomach and the other dissolves in the intestine. Because some drugs have a strong stimulating and harmful effect on the stomach, they will not cause harm to the intestines. Therefore, for this part of the drug, it is necessary to make this intestinal capsule.